Over-the-counter acne treatments are not always appropriate for the lips. Ingredients such as benzoyl peroxide or salicylic acid can be too harsh for this sensitive skin, causing dryness, burning, or cracking without addressing the underlying cause.
If the bumps persist for several weeks, frequently recur, or are accompanied by pain, fever, ulcers, or swollen lymph nodes, you should consult a healthcare professional or dermatologist. A medical examination can help distinguish harmless Fordyce spots from viral infections, cysts, allergic conditions, or other skin disorders that may require specific treatment.