
Neuroscientist Explains How to Remove ‘Brain Waste’ — And Why It Could Help Prevent Dementia
Did you know your brain has its own built-in cleaning system? According to leading neuroscientists, your brain actually “cleans” itself while you sleep — flushing out waste products that, if left behind, may contribute to dementia and Alzheimer’s disease.
Now, experts are revealing how to support this natural process and keep your brain functioning at its best — even as you age.
What Is “Brain Waste”?
Throughout the day, your brain cells produce metabolic waste, including beta-amyloid — the sticky protein that builds up in the brains of people with Alzheimer’s.
If this waste isn’t cleared properly, it can accumulate between brain cells, disrupt communication, and trigger inflammation — all of which are linked to cognitive decline and memory loss.
The Brain's Cleaning Crew: The Glymphatic System
A neuroscientist at the University of Rochester, Dr. Maiken Nedergaard, discovered a powerful system called the glymphatic system, which functions like the brain’s night shift janitor.
“Think of it as the brain’s plumbing,” she explains.
“It kicks into high gear while you sleep, flushing away toxins and waste that build up during the day.”
This system is most active during deep sleep, particularly during slow-wave sleep, the most restorative sleep stage.
How to Boost Brain Detox and Lower Dementia Risk
Here’s what neuroscientists recommend to help your brain clear out waste more efficiently:
1. Prioritize Deep Sleep
Aim for 7–9 hours of quality sleep per night. Sleep is when the glymphatic system is most active.
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Keep your bedroom cool and dark.
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Stick to a regular sleep schedule.
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Avoid screens and caffeine before bed.
2. Sleep on Your Side
Interestingly, studies in rodents show that side-sleeping may help the brain clear waste more effectively than sleeping on your back or stomach.
3. Stay Hydrated
Dehydration can slow down circulation and limit your brain’s ability to remove waste.
4. Exercise Regularly
Physical activity boosts blood flow and supports brain health, which in turn supports waste clearance.
5. Avoid Alcohol and Smoking
Both can impair sleep and reduce the brain’s ability to self-clean.
The Bottom Line
Many people are unaware that their brain performs a crucial “cleansing” process while they sleep — and that poor sleep habits can interfere with this, possibly raising the risk of dementia in the long run.
Turns out, protecting your brain may be as simple as getting better sleep.
So tonight, don’t just sleep — sleep with purpose. Your future brain will thank you.
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